Have you ever wondered why one person might lose weight while the other gains weight on the same diet? Although the answer to this question rests mainly in the differences of the human body, i.e., no two people are identical in DNA structure, there supposedly exists a single fat-burning gene deep within our cells that boosts metabolism. Regardless of the type of food consumed, this switch must be turned on to re-ignite a sluggish metabolism, insists the team at All Natural Nutrition. Do you want to hear their theory of the ongoing tale of losing weight and fat? The purpose of this review is precisely for that, and it technically revolves around a solution called LEANGene.
What is LEANGene?
LEANGene is a support formula to increase the body’s resting metabolism. Using eight powerful ingredients, the team managed to create a supplement that resists fat formation and, in its place, increases fat burning. LEANGene is especially helpful in cases where an inflammation factor introduces obesity. Are you curious to see how inflammation might be brought down to the minimum using merely natural ingredients? Let’s investigate the LEANGene mechanism.
How does LEANGene work?
LEANGene has been formulated to turn on the master “Lean Gene,” controlling part of the metabolism that burns fat while asleep. It is deemed five times more potent than AMPk and ten times more potent than the human growth hormone. All-in-all, the hidden problem that keeps most people from losing weight has to do with the UCP2 gene.
UCP2 is a protein-coding gene tasked with overseeing the metabolism of energy, adipose tissue, and weight management. It has also been associated with decreased reactive oxygen species (ROS), oxidative stress, and inflammation, leading one team of researchers to avow that “UCP2 could link obesity and inflammation .”
ROS as an inflammation marker is known to trigger lipid production and adiposity. This makes the activation of UCP2 vital, especially seeing how the latter is related to body weight, BMI, body composition, fat mass, and lean body mass. So, what does the regulation of the UCP2 gene in bodily cells entail?
All Natural Nutrition, LEANGene, discourages an amino acid called leucine because it releases the insulin hormone (i.e., fat-storing hormone). Individuals might be cursed with increased belly fat, stomach bloating, or even increased water retention. Worst of all, a rise in insulin levels supposedly implies a temporary shutdown in UCP2. For ongoing activation, certain plants and herbs must be consumed, all of which can only be found in LEANGene.
What ingredients are inside LEANGene?
Each LEANGene serving (i.e., two capsules) contains the following main ingredients:
Yerba Mate (250mg)
Yerba mate is an herbal tea made using the leaves and twigs of a plant called Paraguariensis. In the context of LEANGene, the herb’s anti-inflammatory property is highly renowned. One study investigated the effects of yerba mate on insulin resistance and inflammatory markers in mice with high fat diet-induced obesity. These subjects were either grouped into a standard or high-fat diet, and after 12 weeks, they were randomly assigned to one of two treatment conditions (water or the herb). The researchers discovered the herb’s “potential anti-inflammatory effect mediated through an NF-kB pathway,” adding that it restored insulin receptor signaling .
Trimethylglycine, also called betaine anhydrous, is a substance produced naturally in the body. It contributes to liver function, cellular reproduction, and carnitine production and aids in metabolizing the homocysteine amino acid . A double-blinded study including female athletes with prior structured resistance training experience looked at the effects of betaine consumption. In the end, the researchers reported significant changes in lean mass, muscle thickness, body fat percentage, fat mass, and other physical markers. Together, these results led the team to conclude that betaine may enhance reductions in fat mass but not absolute strength .
Magnesium, Calcium, and Sodium Beta-Hydroxybutyrate (100mg, 100mg, and 50mg, respectively)
Beta-hydroxybutyrate (BHB) is a type of exogenous ketone. Like in the case of keto supplements, exogenous ketones help the body to remain in a metabolic state called ketosis. Specifically, the body directs the liver to break down stored fat when carbohydrates are absent. The resulting by-products, aka ketones, now serve as the replacement for glucose. In the case of carbohydrates, anything in excess will be stored as fat. Such an issue doesn’t arise with BHB, as it aims to produce energy from fat. Binding BHB to magnesium, calcium, and sodium to increase hydration and recoup lost minerals.
Grape Seed Extract (100mg) & Resveratrol (50mg)
Grape seed extract (GSE) is made using the seeds of wine grapes. The antioxidants in GSE are trusted to help alleviate oxidative stress, inflammation, and tissue damage, explains one source . Primarily, studies have demonstrated its ability to reduce LDL oxidation triggered by high-fat diets, improve collagen levels and bone strength, and support brain and kidney function, among others.
As for the exact mechanism, a 2020 study highlighted that “GSE exerts its beneficial effects on metabolic syndrome by scavenging intestinal ROS, thus reducing oxidative stress, increasing epithelial barrier integrity, and decreasing intestinal inflammation .” Finally, individuals can anticipate this formula to house resveratrol, which is a chemical found in grapes.
Green Tea Extract (100mg)
Green tea leaf extract is a supplement derived from the Camellia sinensis plant. This ingredient houses several antioxidant properties like the grape seed, making it superior among all extracts. As we searched for answers, one study found that green tea extract upregulated the UCP3 gene, but it did not promote weight loss . So, what is the difference between UCP2 and UCP3?
UCP2 is supposedly distributed across a wide range of tissue and cell types, whereas UCP3 is mainly restricted to skeletal muscle and brown adipose tissue . In general, brown adipose tissue is an ideal type of fat, as it contains many more mitochondria than white fat. Increased muscle mass also restricts fat content. From its looks, green tea extract takes a different route to deal with metabolic function and body composition.
Ceylon Cinnamon Bark (100mg)
Cinnamon bark is perceived as a medicinal global plant with positive effects in reducing blood pressure, plasma glucose, obesity, and ameliorating dyslipidemia . Regarding the link between this ingredient and obesity, one source gave credit to its anti-inflammatory and antibacterial properties . It is important to note that cinnamon alone will not lead to long-term weight loss. This ingredient must be added to a healthy diet and exercise plan.
Inositol is sugar made in the body and can be obtained from certain food groups. Found in nine forms, its main role entails balancing certain chemicals in the body to help with mild mental conditions . When paired with choline, the synergy might give rise to fat burning and prevent excessive liver accumulation of cholesterol and triglycerides. Bear in mind that the latter outcomes are based on a study conducted on myoinositol deficient rats .
Supporting ingredients include Choline (80mg), Calcium (15mg), Magnesium (10mg) and Chromium (100mcg).
Frequently Asked Questions (FAQs)
Q. Is LEANGene safe?
A. LEANGene is a natural supplement that has been manufactured in an FDA-approved, GMP-certified facility under stringent guidelines; hence, it is deemed safe to take.
Q. Who should refrain from taking LEANGene?
A. For safety reasons, individuals are asked to refrain from exceeding the recommended serving. Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should either refrain from taking LEANGene altogether or consult a healthcare professional beforehand.
Q. How should LEANGene be taken?
A. Two LEANGene veggie capsules should be taken once daily as a dietary supplement. For best results, each serving should be taken 20 to 30 minutes before a meal with 8 ounces of water or as directed by a healthcare professional.
Q. What are the purported benefits of taking LEANGene?
A. LEANGene is anticipated to activate the UCP2 gene, which in turn might assist fat burning and support healthy blood glucose levels and healthy metabolism.
Q. What if LEANGene doesn’t work as intended?
A. If LEANGene fails to deliver as advertised, customer service must be contacted for a full purchase price refund. For full details on the particulars of the 60-day money-back guarantee, reach the team at:
What does each LEANGene purchase include?
Along with each LEANGene purchase, individuals will get instant access to three special reports. These have been compiled to further assist in the fat-burning processes. Below is a summary of the contents of each guide:
Special Report #1: The 7-Day Perfect Body Blueprint
Inside the first special report, the team plans to reveal the truth behind achieving the perfect body. It is a 7-day process intended to melt away 10 pounds of ugly fat and trapped water overnight (hint: it involves tweaking food and water intake).
Special Report #2. 24-Hour, Stop Your Fat Storage Gene Plan
Although individuals are not required to make dietary changes to optimize the UCP2 gene, doing so might reveal results sooner. Additionally, factoring in diet might increase energy, and promote healthy HDL cholesterol levels and heart health, say the least. To put everyone on the right path, details on how to make dietary changes will be listed in this report.
Special Report #3. Stop Fat Storage Tonic & Smoothie Recipes
The team pledges to have discovered smoothie recipes that target UCP2 while getting rid of extra belly fat. For the specifics, individuals are encouraged to read through the recipes and to give each one a try!
How much does LEANGene cost?
Every bottle of LEANGene includes 60 capsules, enough to last one month. Since time is needed to activate the UCP2 gene, the team wanted to encourage intermediate uses by offering the following discounts:
- One LEANGene Bottle: $59.00 Each
- Three LEANGene Bottles: $49.00 Each
- Six LEANGene Bottles: $44.00 Each
Ultimately, LEANGene has been designed to target a particular gene called the UCP2 gene (aka lean gene) linked with obesity. Our editorial team was generally pleased with the scientific evidence in researching the included ingredients. Although some ingredients do not have strong enough support, the fact that preliminary results exist permits researchers to dive deeper into means of activating UCP2.
Some of the key benefits include fat burning at rest, boosting metabolism and energy levels, and a noticeable difference in body composition when taken as directed. Are these benefits guaranteed? It really comes down to each person, but fortunately, there is a money-back guarantee, making it risk-free for 60 days. The next step is to confirm the makers of this supplement. We see that it is All Natural Nutrition; however, very little has been disclosed on the company background.
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