Best Weight Loss Pills UPDATE

As we enter the new year, many of us (our editorial team included) are likely to get started on our set goals to reach. One that rarely leaves such a list is weight loss. Fortunately, the supposed fact that diet and exercise are the only driving forces for a successful weight loss journey has been debunked. Factors including age, health conditions, family history, race, and eating habits need to be accounted for. This is not to say that developing a healthy eating habit or exercising doesn’t work. Instead, we were going in the lines of including an extra push. In what form are additional motivations available? We were thinking of weight loss supplements.

On their own, weight loss supplements are meaningless, as they only have enough power to induce marginal results typically. However, when paired with a healthy lifestyle, individuals may have a chance at scratching off weight loss from their new year’s list. Taking everything into account, the purpose of this review is to unearth what our editorial team believes are the best weight loss supplements, pills, and powders of 2022. Not one, but a whopping 28 were qualified either based on our customizable ranking system or due to increased popularity. Before delving into the specifics, here’s a quick breakdown of each solution at hand!

The Top Weight Loss Contenders of 2022

From thousands of supplements, our team could bring the number down to 28. Does this mean that all 28 are worthy contenders? The only way to find out is by analyzing each one using a series of factors ranging from the ingredients down to the manufacturer and everything in between. Without any further delay, here are the picks:

  • Exipure
  • Java Burn
  • Lanta Flat Belly Shake
  • AcidaBurn
  • Adimin
  • Alli®
  • BioFit
  • Biotox Gold
  • Keto Elevate
  • BurnXT
  • CarboFix
  • Cellucor Super HD
  • HourGlass Fit
  • IKARIA Lean Belly Juice
  • IKIGAI Weight Loss Formula
  • Instant Knockout Cut
  • KetoCharge
  • LeanBean
  • Lean Belly 3X
  • Meticore
  • Okinawa Flat Belly Tonic
  • PhenQ Pills
  • PhenQ Meal Shake
  • ReIgnite
  • ReNew Weight Loss Detox
  • Revitaa Pro
  • Luminae


  • Company: Exipure
  • Starting Price: $59

Exipure is a weight management supplement reckoned to eliminate the root cause for weight gain, i.e., white adipose tissues (WAT). The body’s fat content can be broken down into two types, WAT and brown adipose tissues (BAT). Ideally, there should be more BAT than WAT in the body; otherwise, fat gain issues will arise. Dr. James Wilkins and John Barrett formulated Exipure using plant-based nutrients to reverse such breakdowns. That way, BAT levels will be activated, while some form of browning of WAT levels can also be expected.

Each serving (i.e., one capsule) embodies the union between 300mg of eight exotic ingredients that include Perilla Leaves, Holy Basil, White Korean Ginseng, Amur Cork Bark, Quercetin, Oleuropein, Propolis and Kudzu Root. Fortunately, there’s more to one’s purchase than Exipure bottles. Precisely, individuals who place bulk orders will also receive “1-Day Kickstart Detox” and “Renew You” guides. Although the effort in providing resources must be appreciated here, we still need more information about how Exipure works to convert WAT into BAT using brown fat-boosting ingredients. One of the only major downsides of Exipure being the best weight loss pills for 2022 is the exact concentrations of the ingredients are not known due to the proprietary blend. And to top it off, the top-rated weight loss formula comes with an industry-leading 180-day money-back guarantee for all customers.

Java Burn

  • Company: John Barban
  • Starting Price: $49

Another metabolic supplement, namely, a coffee add-on, that qualified for this guide is John Barban’s Java Burn. Deemed a 100% natural and safe solution that encompasses a specific proprietary blend, daily consumption can curb appetite, increase energy levels, and guarantee a calorie deficit for weight loss. The way by which this add-on is said to elicit results is by converting fat storage into free fatty acids. After some steps, free fatty acids promote adenosine triphosphate (ATP) production, consequently increasing energy and weight loss.

The next question to ask oneself is, “What do we know about John Barban?” It turns out that John continues to contribute to the realm of dietary and sports supplements, with this being his eighth year and counting. In reality, his expertise revolves around product development and consultation, which permitted him to establish healthy professional relationships with MuscleTech, NxLabs, Slimquick, ADS, BlueStar Nutraceuticals, and Empowered Nutrition Products. Regarding his certifications, they include NSCA, CSCS, ACE PT, CSEP, along with a Bachelor’s in exercise physiology.

Finally, we have the Java Burn formula, which comprises of Green Tea Extract (300mg), Chromium (20mcg), L-Theanine (100mg), L-Carnitine (100mg), Green Coffee Bean Extract (200mg), Vitamin D3 (20mcg), Vitamin B6 (1mg), and Vitamin B12 (5mcg).

Lanta Flat Belly Shake

  • Company: Claro Nutrition
  • Starting Price: $69

The Lanta Flat Belly Shake is a dual-purpose dietary supplement. To be more precise, individuals can use this solution either as a meal replacement or a metabolism booster. Delivered in powdered form, the Claro Nutrition team believes that fighting off hidden fat around the GLP-1 hormone is the ideal strategy for weight loss. To do this, they had to combine the likes of Mangosteen, Panax Ginseng, Cinnamon Bark, Ashwagandha, and Green, to list a few.

We are told that these ingredients and many unnamed ones can promote weight loss, fat burning, and suppress appetite at the time of writing. In all honesty, the involvement of the fat-wrapped GLP-1 hormone is seldomly introduced when presenting a weight loss supplement, so seeing a new approach captivated our editorial team. But does this mean that we are entirely swayed? The metabolic superfood formula sure is unique and the team behind Lanta Flat Belly Shake supplement has been a leader in the weight loss product formulation industry.


  • Company: Applied Science (AS) Nutrition
  • Starting Price: $79

AcidaBurn is a detox cleanse formula reasoned as having the ability to promote weight loss, energy boost, mental clarity, and healthy digestion. As per the makers of this solution, AS Nutrition, the formula supports clinically tested ingredients designed to induce a weight loss of 0.5lbs per week for ten consecutive weeks. The latter has been argued as being truthful because of AcidaBurn’s ability to drive energy levels, which can help individuals maximize their workouts and bowel movements.

Concerning the company, AS Nutrition insists that they are in the business to “disrupt the supplement industry and [to] shift the focus away from marketing sales pitches to the real science behind why each supplement works.” So, what is their motto? “Apply Science to your Health.” This explains why they take pride in following imperative manufacturing policies, investing in research and development, ensuring their products are 100% vegan for optimal inclusivity, and standing by regular analysis for purity and consistency. Getting back to the AcidaBurn formula, each serving (2 capsules) contains a 1.5g proprietary blend of Psyllium, Bentonite Clay, Black Walnut, Oat, Flaxseed, Prune, Aloe Vera, L. Acidophilus, Apple Pectin, and Glucomannan.


  • Company: N/A
  • Starting Price: $69

Adimin is touted as a weight-loss formula founded on a controversial breakthrough made by a Japanese doctor known for his contributions and accomplishments in science. Specifically, it has been designed to trigger maximum fat burning and healthy metabolic function to progress through their weight loss journey. In a video presentation regarding Adimin, the speaker revealed that toxins are the reason for unwanted fat storage, arguing that weight loss is best among those who target both concerns simultaneously. At the time of writing, we are only told that each serving (probably two capsules) encompasses the likes of Vitamin B12, L-Tyrosine, Ashwagandha, and Schizandra, among others.

However, a natural question that people might ask themselves is, “Why is Adimin a top contender?” It remains a popular choice online, and we wanted to show everyone that they shouldn’t believe everything they see/read on the internet! Why is that? To what extent are we convinced by Adimin? Some might not even by the slightest, and here’s why: a) there is very limited information available about makers of the formula, 2) the supplement facts is not visible and 3) any direct contact (i.e., phone number, mailing address, or email address) cannot be established. But, with a little extra research and digging, it looks like it is relatively easy to contact customer support and even request a refund with the unconditional money-back guarantee. Matter-of-factly, should individuals have any questions, they would have to submit a ticket and will get a response right away. The important part to know with this top rated weight loss supplement is that it is starting to pick up traction and buzz amongst the diet pill community and has a compelling story attached to its origins.


  • Company: N/A
  • Starting Price: $69

ALIVE is a nutritional diet pill that improves one’s metabolism while promoting a reasonably healthy caloric deficit to reach weight loss goals. The unnamed makers argue that this formula works by enhancing dopamine function in the brain. Why is this important? It is a general belief that when dopamine levels are high (implying contentment), it will naturally suppress cravings and increase energy levels. Who can forget the motivation that stems from such a mood? As this is being written, the primary ingredients are Green Coffee Bean Extract, Teacrine, and Guarana.

While the idea behind boosting dopamine for better control checks in coupled with the chosen ingredients, which to date have been commonly used in weight loss supplements, our editorial team was slightly uncomfortable by the lack of transparency in regards to ingredient dosages. Specifically, although may more digging may be required, the makers remain hidden the same way the supplement’s fact is. The aforesaid is upsetting, seeing that ALIVE might have potential the disclosed information holds and is being offered on a very trustworthy platform that adheres to a strict customer-centric refund policy.


  • Company: Alli®
  • Starting Price: $53

Alli® is the only FDA-approved, over-the-counter weight loss supplement available in the market. Created specifically for overweight adults 18 years or older, this supplement supports weight loss when taken alongside a reduced-calorie, low-fat diet. By overweight, we mean anyone who has a BMI of above 25. Our editorial team was drawn by the clinically proven results, suggesting that individuals can lose 10 to 15% of visceral fat (i.e., belly fat) after 24 weeks of use. The active ingredient found inside Alli® is orlistat (60mg), i.e., one that has been extensively studied across the world. Finally, their level of transparency is matchless, as the team has since posted practically every conceivable documentation online!


  • Company: Nature’s Formulas
  • Starting Price: $69

BioFit is a gut health-enhancing dietary supplement advertised as effective for weight loss goals. To date, it remains a popular choice online because of its simple formula encompassing seven fat-burning probiotic strains that have been clinically studied to help optimize digestion and reduce feelings of bloat (to some extent). The idea that the gut needs to be cared for is convincing for weight loss, which is why BioFit saw its growth reach new heights.

Considering everything, the Nature’s Formulas team has been in the business for over 25 years and was established to believe that humans shouldn’t have to turn to traditional drugs and surgery for everything. Truthfully, they insist that such approaches seldomly promote wellness. Based on the claims made, it was only after delving into their research on natural compounds that they made it a mission to spread the word regarding them.

Each serving (1 capsule) introduces the body to the likes of Bacillus Subtilis (DE111™), Lactobacillus Rhamnosus, Lactobacillus Casei, Lactobacillus Plantarum, Lactobacillus Acidophilus, Bifidobacterium Longum, and Bifidobacterium Breve.

Biotox Gold

  • Company: Biotox Nutrition
  • Starting Price: $69

Rarely do we see weight loss tinctures, but here we are, with Biotox Gold. According to a video presentation, this is the first-ever, 100% all-natural liquid drop that delivers not one but 20 detoxifying nutrients and plant extracts. Manufactured in the US, in an FDA-approved and GMP-certified facility, this solution is said to have undergone stringent testing processes to ensure that it is free from dangerous stimulants and toxins. The makers behind Biotox Gold are none other than Biotox Nutrition, but that’s as far as our research led us.

Regarding ingredients, the presentation has been supplemented with scientific resources, which hint at elements such as Garcinia Cambogia, Grapeseed Extract, Capsicum, Eleuthero, and Maca Root. This is nowhere near the supposed 20, and none of the revealed ones have been listed with their respective concentrations at the time of research. Ultimately, it would be great for Biotox Nutrition to be more transparent in regards to ingredients and dosages, but it is one of the most attractive top 22 best weight loss supplements in 2022 due to its all-natural liquid delivery system.

Keto Elevate

  • Company: BioTRUST
  • Starting Price: $34

As hinted in its name, Keto Elevate is founded on the principles of reaching ketosis. The ketogenic diet remains a top contender because the results speak for themselves of all the diets. Yet, the main concern that many have voiced is the impact that eliminating carbohydrates intake tends to have, i.e., short-lived keto flu symptoms.

That said, BioTRUST flourished into existence with the hope of giving back to the community. Co-Founders Joel Marion and Josh Bezoni created a premium nutrition brand online. This team only wants the best for everyone, from choosing ingredients rooted in nature and avoiding junk to abiding by an industry-leading level of quality control and involving third-party lab testing firms.

This is where Keto Elevate comes into the picture. In the case of weight loss, this supplement has been formulated to naturally elevate ketone levels in the body for all the ketogenic benefits (i.e., mental clarity, increased energy, and appetite management). The critical component is a medium-chain triglyceride (MCT), its active compound, Caprylic Acid (C8). Most conventional keto supplements include coconut oil, but they only offer small amounts of MCT, not even the C8.

The BioTRUST team pledges that each serving (i.e., one scoop of 9g) delivers C8 MCT Oil Powder to rectify the quality. Finally, individuals needing more support can reach out to the BioTRUST team for free VIP health and fitness coaching, not to forget a free guide called “The Top 14 Ketogenic Foods.”


  • Company: Jacked Factory Store
  • Starting Price: $29.99

BurnXT is a thermogenic fat burner that works by increasing the body’s heat-producing capacities. In so doing, our metabolic function is believed to become supercharged, eventually giving rise to healthy bowel movements. We were surprised to see that this formula remains a #1 best-seller on Amazon, and this comes after a steady success for over three years.

Established in 2014, Jacked Factory Store values people who train hard day in and day out while constantly challenging themselves. The latest indication of effort signifies one’s determination, which the Jacked Factory Store team insists should be reinforced with supplements that work. Seeing the discrepancies in the market, the team took matters into their own hands to develop the “most premium, hard-hitting, effective supplements.”

As described on the official website, “Our products are formulated using the best science-backed ingredients and tested in the trenches,” emphasizing that “Jacked Factory products contain nothing but research-supported ingredients in effective doses.”

Each serving (1 capsule) of BurnXT is said to deliver an ample concentration of Acetyl-L-Carnitine HCl (350mg), Green Tea Leaf Extract (225mg), Caffeine Anhydrous (135mg), Capsimax® Cayenne Pepper (25mg), and Bioperine® (2.5mg).


  • Company: Gold Vida
  • Starting Price: $49

CarboFix is a carbohydrate management formula that secretes healthy blood glucose levels and improves glucose uses. When taken as directed, individuals can anticipate a healthy increase in fat-burning, weight loss, and longevity. Additionally, those who have struggled with appetite fluctuations in the past can now find a way to make amends thanks to this formula’s ability to suppress hunger altogether.

How are any of these results possible? It turns out that CarboFix factors the need to activate our AMPK pathway in the body. When this piece of the puzzle is inactivated, that’s when more fat is allegedly stored. Undoubtedly, individuals are naturally left with reduced fat oxidation rates. Based in Canada, the Gold Vida team believes that to get AMPK rolling as intended, each serving (i.e., one capsule) must embody the likes of Chromium Picolinate (200mcg), Berberine HCL (400mg), Cinnamon Bark (100mg), Benfotiamine (80mg), Naringin (50mg) and Alpha Lipoic Acid (50mg).

We must disclose that very little is known of Gold Vida besides its place of operations. Hence, we encourage everyone to contact customer service before placing an order with any questions or concerns.

Cellucor Super HD

  • Company: Cellucor
  • Starting Price: $29.99

Cellucor Super HD is a high-definition, thermogenic fat burner that equips the body with antioxidant and fat-melting properties. In turn, individuals will experience heightened weight loss results and a surge in energy and mental focus. Like most companies, Cellucor is a firm believer in focusing on the body, or as they put it, in terms of what is consumed and physical activity. While the team explained that the duo is essential, “if you take a step back, you’ll notice there’s more to it.” A formula like Super HD is added, where only the “best” is offered.

For 15 years and counting, Cellucor has been on a mission to aid consumers in their fitness journeys. Precisely, they want everyone to know that they want to “help you rise to the challenge, to obliterate indecision, to help you stare down what holds you back.” What better way to do this than by becoming “the best sports nutrition brand in the world, delivering the most-effective, best-tasting, and highest-quality products for you”?

On that note, each serving (1 capsule) includes a 250mg-SuperHD ThermoSculpting™ Blend (Green Tea, Slimpro® Protein Hydrolysates of Blue Whiting, and Dandelion Root), a 250mg-SuperHD Sensory Impact™ Blend (N-Acetyl-L-Tyrosine, Rhodiola, Amla, Yohimbe, Capsimax® Cayenne Extract, Evodia, Toothed Clubmoss, and Rauwolfia vomitoria) and Caffeine Anhydrous (160mg).

HourGlass Fit

  • Company: HourGlass Fit
  • Starting Price: $55

HourGlass Fit is a caffeine-free weight management support for women looking to melt away fat. In so doing, their toned, shaped, and “sexy physique” can finally be revealed. Unlike most fat burners, the twist with this one is caffeine-free. After some thought, the team created a formula that delivers in three ways. First, HourGlass Fit helps to reduce calories. As explained, “To get rid of […] fat you’ll either need to eat less to generate a calorie deficit or burn [calories].” Second, it boosts energy, yet another way to burn more calories. Finally, the creators ensured that each serving beats cravings (the fewer cravings one experiences, the less likely one might consume unnecessarily). Here’s what the HourGlass Fit team wants women to know about their strategy,

“We’ve carefully considered the wellness needs of women to deliver a natural supplement which is powerful and proven, yet gentle enough for daily use […] Unlike caffeine-based fat burners, Hourglass Fit users report no nasty side effects […] No unpleasant aftertaste or clumpy powders.”

So, what guarantees results if an ingredient like caffeine is removed entirely? Simple, as long as each serving (i.e., 4 capsules) includes Vitamin B6 (1.7mg), Vitamin B12 (2.4mcg), Chromium (125 mcg), zinc (8mg), Vitamin B2 (1.1mg), Konjac Root Extract (3g), Capsimax® (100mg), Bioperine™ (5mg) and 5-HTP (150mg), there should be no problem.

IKARIA Lean Belly Juice

  • Company: IKARIA
  • Starting Price: $69

The IKARIA Lean Belly Juice is a metabolic formula encompassing an advanced superfood complex. This strategy is backed by scientific studies, pointing towards increased fat oxidation, fat burning, energy levels, and healthy digestion. Furthermore, individuals may notice a reduction in cravings and some level of support regarding blood pressure and joint health. Unlike the conventional pills, we’re now looking at a powdered weight loss supplement that simply needs to be mixed into water or a beverage of choice.

The IKARIA team makes their case for choosing superfoods by introducing the culprit for stubborn fat, i.e., uric acid. When uric acid levels are higher than usual, more challenges will present themselves in the form of exhaustion, poor digestion, and uncontrollable weight gain. With the IKARIA Lean Belly Juice, these levels can be optimized for healthy weight loss. While very little is available on the makers, we have been shown a glimpse into the formula.

Specifically, each scoop celebrates the coming together of Fucoxanthin, Silymarin, Dandelion, Resveratrol, Citrus Pectin, and Capsaicin. As much as the straightforward nature of this formula excites our editorial team, we cannot make any more comments without the supplement facts. For a solution to be backed by science naturally implies dose-dependent results, and to see that this has not been revealed is quite a shame!

IKIGAI Weight Loss Formula

  • Company: Dr. Hiro Ichikawa, Co-Founder of IKIGAI
  • Starting Price: $59

The IKIGAI weight loss formula is believed to target yet another root cause for weight gain, i.e., stress. By the looks of it, stress not only introduces binge-eating but can go as far as increasing blood pressure levels and heartbeat. These consequences are a result of rising cortisol levels. For those of you who are unfamiliar with cortisol, it is our stress hormone. It has been linked with weight gain due to its ongoing relationship with the insulin hormone. As cortisol increases, our cells become resistant to insulin. Unfortunately, this increases blood sugar levels, leading to weight gain.

To resolve those described above, the IKIGAI Weight Loss Formula was created using the principles of Japanese culture and plant-based medicine. In other words, 24 ingredients are found in this supplement, of which six are known, Rhodiola Rosea, Ashwagandha, Chamomile, Lemon Balm, Valerian, and Bacopa Monnieri. Once again, the strategy is substantial, but the lack of transparency (the maker’s credentials and supplement’s fact) makes us question the entirety of the supplement.

Instant Knockout Cut

  • Company: Roar Ambition
  • Starting Price: $59

For fitness fanatics looking to supercharge their results, the Instant Knockout Cut is a dietary supplement to have. Touted for its acceptance of scientifically backed ingredients likely to help individuals reach a desired level of leanness, the mechanism through which results are unraveled involves thermogenesis.

Aside from leanness, the Roar Ambition team insists that their methodology can also increase fat burning and an excellent curb to one’s appetite while motivating one towards a healthier lifestyle. These facets are what helped this company flourish into one that provides products created in “high class facilities in the USA and UK and shipped from there too.” Moreover, they shared that their supplier’s aid in “creat[ing] [their] high-end supplements.”

Each serving (4 capsules) brings together the likes of Vitamin D3 (45mcg), Vitamin B6 (5mg), Vitamin B12 (10mcg), Glucomannan (1800mg), Green Tea Extract (500mg), Caffeine Anhydrous (300mg), L-Theanine (100mg), Cayenne Powder (100mg), and Black Pepper (10mg).


  • Company: Wolfson Brands (UK) Limited
  • Starting Price: $59.95

KetoCharge is Wolfson Brands’ take on a ketogenic dietary supplement that releases stored fat for energy, raises blood ketone levels and eliminates keto-flu symptoms. As introduced earlier in this piece, the moment the body reaches ketosis, it relies on stored fat for ketones, delivered through the bloodstream to several of our cells, tissues, and organs, among other components.

Bear in mind that the diet alone tends to instill a wait time of 3 weeks. That’s why KetoCharge is much needed, as the fat-burning processes can commence as early as a day (if all other factors are up to par). That said, each serving has been created to provide 800mg of exogenous potassium beta-hydroxybutyrate (BHB). The latter mimics the role of naturally produced ketones while keeping everyone hydrated.

Concerning the faces of KetoCharge, CEO of Wolfson Brands (UK) Limited, Stewart Lochrie wants everyone to know that this solution is a result of the coming together of experts with unique backgrounds. The one similarity that brought them together is each member’s yearning to “inspire positive lifestyle change[s].”


  • Company: Ultimate Life
  • Starting Price: $59.99

LeanBean is a dietary supplement designed specifically to tend to the needs of female fitness models in search of extra support in burning fat quickly and safely. With emphasis placed on scientific findings surrounding weight and fat loss, the Ultimate Life team has since formulated LeanBean using ingredients such as Vitamin B6 (3.72mg), Vitamin B12 (6.4mcg), Chromium (120mcg), Green Coffee (6g), Acai Berry (800mg), Green Tea Extract (200mg), Turmeric (200mg), Glucomannan (500mg), Garcinia Cambogia (400mg), Cayenne Powder (60mg), Black Pepper (20mg), and Raspberry Ketones (8mg).

So, why might one consider Ultimate Life? This team intends to support women without pushing them to spend a fortune. At the same time, they want to assure everyone that natural nutrients fit into practically any plan and are more likely to drive results efficiently than others. While we were initially given the impression that LeanBean is only for fitness fanatics, that isn’t entirely the case. Their solution supposedly took a specific path, which later broadened to factor in other types of women.

Lean Belly 3X

  • Company: Beyond 40
  • Starting Price: $59

The Beyond 40 husband-wife duo addressed weight loss by creating a solution that reduces inflammation, promotes healthy blood sugar levels, and proficiently breaks down fat cells for belly-trimming and toning purposes. Dubbed the Lean Belly 3X, it employs the concept of destroying bad fat with good fat. Each serving (2 softgels) is said to rejoice over Safflower Seed Oil (1500mg), Conjugated Linoleic Acid (1200mg), and BioPerine® (5mg); we don’t think it can get any more candid than this.

As for the husband-wife duo responsible for Beyond 40, Shaun and Karen Hadsall initially started their respective wellness journeys and found how much a positive difference it made in their lives, both of whom are happy today and are well into their 60s. Understanding the struggles and potential hindrances others may face, the duo decided it only made sense for them to start a company with the mission of helping everyone achieve the best possible self for the best possible life.


  • Company: Meticore
  • Starting Price: $59

Meticore is a dietary supplement established on the belief that raising internal body temperatures induces weight loss results. Designed to support people of all works of life, the makers avow that the Meticore formula will enhance metabolic function like never experienced before. For the team to have reached such lengths is impressive, but what’s more impressive is the supposed ingredients that normalize body temperature. Notably, individuals can anticipate ingesting Turmeric, African Mango, Ginger, Moringa, Bioflavonoids, Fucoxanthin, Vitamin B12 (10mcg), and Chromium (35mcg).

There’s good news and bad news. Starting with the good news, the science behind the concept of raising body temperatures checks in for weight loss. Thankfully the makers decided not to leave the supplement fact’s hidden, and have a very transparent brand and ordering platform to use. When Meticore weight loss pills first became available in October 2020, it was the hottest fat burning formula to lose weight in the month of January 2021. The morning metabolism trigger is well worth a look and should still be considered one of the best weight loss pills that work due to its ability to target low core body temperatures.

Okinawa Flat Belly Tonic

  • Company: Flat
  • Starting Price: $89

The Flat team got together in the hopes of launching a solution that celebrates healthy weight management, digestion, and shooting energy levels through the roof. What might such a solution look like? Referred to as the Okinawa Flat Belly Tonic, a dietary supplement that succeeds those described above is equipped with ingredients that even vegans can add to their routines.

In terms of the chosen ingredients, we do know that they entail Green Tea, Inulin, Momordica Charantia, Hibiscus Sabdariffa, Acai Berry, and Aronia Berry. We must mention that there are several suppliers for this supplement. Verified customers on Amazon argued discrepancies in the supplement facts. So, careful research must be conducted to guarantee that the Flat team develops the purchased product.

PhenQ Pills

  • Company: Wolfson Brands (UK) Limited
  • Starting Price: $69.95

Wolfson Brands makes a reappearance through a brand that it oversees called PhenQ. The PhenQ dietary supplement is touted for housing scientifically-backed doses for fat burning, feelings of satiety, healthy mood, and energy levels and ultimately barricading the risk of developing fat production. The team claims to have gone with ingredients that have been proven to elicit results. Factually, each serving (2 capsules) contains L-Carnitine Fumarate (150mg), Caffeine anhydrous (142.5mg), A-Lacys Reset (25mg), Nopal (20mg), Capsimax (8mg), Piperine Extract (3mg), and Chromium (10mcg).

PhenQ Meal Shake

  • Company: Wolfson Brands (UK) Limited
  • Starting Price: $53.90

Keeping the ball rolling up next from PhenQ is the team’s take on a Meal Shake. What have they reflected upon in creating this shake? It turns out that the team made sure to create a solution that can re-ignite a decelerated metabolism, all while turning on the switch to our AMPK levels. Therefore, fat burning is not only guaranteed to a large extent, but so is the absorption of fundamental vitamins, minerals, and adaptogens. Each serving delivers 16g of vegan protein and 13g of healthy fats based on the supplement’s fact. Finally, when analyzing things from the ingredients’ perspective, each serving supports the likes of KSM-66 Ashwagandha® (300mg), InnoSlim® (250mg), Pea Protein (12g), MCT Coconut Oil (13g), Reishi Mushroom Extract (100mg), Linseed Flour (11g), Hemp Protein (1.5g), and Brown Rice Protein (1.5g), all of which might reduce belly fat by a whopping 11%.


  • Company: N/A
  • Starting Price: $69

Next, we have ReIgnite, a dietary supplement that boosts mitochondria for healthy fat burning. Mitochondria make our cells’ ATP compositions, i.e., a fundamental energy source. As explained earlier, this production kickstarts metabolic function, which might help individuals lose weight. The approach involves numerous steps before the final result; therefore, time is required to notice any changes. Getting right to the ingredients list, we are told that each serving (2 capsules) includes Kucha Tea, Apple Cider Vinegar, Pomegranate Extract, Ginger, Turmeric, Gardenia, Black Cumin, Chromium, Black Pepper, Fucoxanthin, and Berberine.

Considering everything, a couple of things did not sit well with us. For starters, the makers have neither revealed themselves nor discussed manufacturing matters. Then there’s the ingredient list, which is nice to have, but listing what’s inside without providing a detailed breakdown is beyond meaningless. For these reasons, we ask everyone to resort to customer support before proceeding with an order.


  • Company: James Marshall
  • Starting Price: $59

Another impractical detox formula that supposedly controls appetite for weight loss is the ReNew dietary supplement. Why do we think this way? The makers insist that this solution is a “3-second ritual [that] melts fat overnight”. This form of advertising is done merely to deceive individuals into placing an order. Besides those described above, the supposed ingredients include Psyllium Husk, Magnesium, Green Coffee Bean Extract, and African Mango Seed Extract. Are these everything? We wouldn’t know since no supplement facts with an appropriate breakdown of ingredients have been provided. Finally, we are told that ReNew was formulated by a physical therapist, James Marshall, yet we could not verify that he is who he claims to be. For these reasons, we ask everyone to do their due diligence before moving forward.

Revitaa Pro

  • Company: N/A
  • Starting Price: $89

Revitaa Pro is a weight loss supplement designed to initiate weight loss by first rectifying cortisol levels in the body. Undoubtedly, this isn’t the first time seeing how significant stress can be on not just weight loss but other areas of health as well. The main ingredient found inside Revitaa Pro is Resveratrol extracted from the Japanese knotweed (600mg). Studies on the ingestion of resveratrol on weight loss have concluded that it can significantly reduce weight, BMI, waist circumference, and fat mass. Additionally, it might positively affect the leptin hormone associated with satiety. Other probable benefits stem from its antioxidant and anti-inflammatory properties. For now, insufficient details are available on the makers, which is unfortunate given that their direction is pretty justifiable.


  • Company: SANE Laboratories
  • Starting Price: $67

Luminae is a weight loss support deemed the “next generation nutraceutical.” In what ways? First, the ingredients found inside Luminae coupled with a healthy diet and exercise-induced weight loss. Second, it naturally promotes fat burning rather than fat storage. Third, this is one of the few solutions on the market to be stimulant-free. The last and most fundamental of them all is the mere fact that this formula has been clinically proven to work.

Operating within the realm of health and wellness since 2014, our editorial team was satisfied by the SANE Laboratories team’s commitment to finding the latest research. Forget high costs and vagueness, as this team wants consumers to next-generation from the source of ingredients and manufacturing stages right down to lab testing. Interestingly enough, the company has even gotten heads turning because it was listed on Inc. 500’s list of America’s Fastest-Growing Private Companies. As for the ingredients list, each serving (1 capsule) contains Niacin (20mg), Calcium (100mg), a 345mg-proprietary blend (Green Tea Leaf Extract, and Grapefruit Seed Extract), and a 145mg-Procolase™ proprietary blend (7-Keto® DHEA, and Bromelain).

The Ranking System That Tells All Untold Stories

Several perspectives on weight loss can be found across all the top contenders of 2022. Some targeted stress, while others dove deeper into the structure of bodily cells. A select few even went to places that companies seldomly go. Therefore, individuals might wonder how our editorial team arrived at these 28 solutions. It all started with a ranking system that distinguishes between different weight loss solutions. While it can be customized to one’s likings, we decided to include the following in ours:

Company & Transparency

Having knowledge of the company behind a particular solution is imperative, as it reflects their efforts in ensuring that consumers are getting a safe and effective solution. Given how saturated the internet is regarding different ingredients, just about any solution can take form. Should individuals stumble upon one that lacks company information and transparency the same way we did in numerous instances above, it’s a sign that should not be neglected.

Scientifically Backed Ingredients at Clinically Effective Doses

Weight loss supplements are like fat burners in the sense that they have a history of stirring a lot of conversations, both good and bad. Some sources insist that weight loss pills are bogus, while others celebrate them. Due to mixed findings, our editorial team wanted supplements to check off two boxes ideally; the first is for scientifically backed ingredients, and the second is for clinically effective doses. If a supplement is said to comprise of scientifically backed ingredients, not only should the makers reveal the source, but they should also maintain the reported doses. If the latter is not satisfied, the solution should be pushed to the end of the list.

Advertised Benefits

The advertised benefits need to be sensical to proceed with a product. Any solution broadcasted as powerful enough to induce weight loss overnight is unnatural. The average consumer can expect to lose up to 15lbs a month (and this is a stretch as it is) should they commit to a healthy diet and good exercise regime. No pill, powder, or shake can replace hard work, which must be instilled in everyone’s minds!


Popularity is rarely factored into ranking systems, but our editorial team went with it anyways. Our intention was never to avow that a popular supplement is good. Instead, we wanted to prove that not all popular solutions are what they are advertised to be. A handful of the top 2022 contenders are popularly in-demand online yet fail to meet the most basic requirements. These should be avoided at all costs because they are nothing more than complete money grabs!


Uniqueness is an umbrella term for practically anything that sets a brand apart from others. Whether it entails scientific evidence, formulation by doctors, third-party lab testings, money-back guarantees, educational resources/guides, or the act of giving back, we greatly appreciated them. These additional measures help us choose between two or more identical formulas.

Verified Customer Reviews

Verified reviews provide some insight into a supplement under consideration. Specifically, we were going for possible cons surrounding the supplement and the extent to which one might be faced with a health compromise. In the latter case, the solution was ignored because we would never want to introduce anything with even the slightest risks.

Value for Money

Lastly, we have value for money as a factor. This factor depicts the number of boxes checked off from the ranking system. Our general belief is that price alone rarely paints enough about a solution. If truth be told, this guide alone proves that some of the higher prices are supported by nothing but deception and lack of transparency. Moving forward, we ask everyone to review benefits in terms of costs as a last resort.

What does Science Suggest About Weight Loss Supplements?

We finally arrive at the most thought-provoking part of this guide, i.e., where does science currently stand regarding weight loss pills. From above, individuals may have noticed that specific formulas encompass identical ingredients. Our editorial team was curious to see whether there is any reason to believe that those in common are effective.

Of course, when individuals do their respective research, they must focus on everything found within the formula. In our case, this could take quite some time, seeing that we have 28 top contenders to discuss. Hence, we took the top 5 common ingredients and orlistat as the sixth one under review. Why? It is a big deal for a solution to be approved by the FDA, so why not see what makes the latter stand out from the former. Bearing everything in mind, here’s what we discovered:

Green Coffee Bean Extract

Green coffee bean extract comes from coffee beans that haven’t undergone roasting processes. The main advantage here is that the extracts will now have many chlorogenic acids. We stumbled upon a piece by WebMD where the professor of chemistry at the University of Scranton, Joe Vinson, was interviewed. Vinson and his colleagues allegedly administered participants 700mg or 1050mg of green coffee bean extract over a 22-week study period. In between, these participants had wash-out periods where they were not required to consume any supplements.

By the end, body weight declined by an average of 10.5%, while body fat declined by 16%. The group experienced slightly more weight loss with the higher dose. Vinson explained that “[Chlorogenic acid] may have some effect on keeping down glucose absorption which in turn helps reduce weight [1].” A more recent study looked to explore the effects of chlorogenic acid on fat reduction coupled with its underlying mechanism. Over four weeks, the researchers found that fat accumulation in the liver and blood lipid levels dropped using a mice model. They also discovered that these results are related to the PGC-1alpha/UCP-1 pathway [2].


Capsimax® is a capsicum extract (derived from chili peppers) delivered in bead technology to prevent oral and gastric burning. As we searched for more clarity, we crossed paths with a study that evaluated the effects of capsaicinoids (CAPs) on body fat and fat mass while accounting for interactions with body habitus, diet, and metabolic propensity.

Participants received a placebo, 2mg of CAPs, or 4mg of CAPs over 12 weeks. After the 12-week mark, researchers learned that they lost 5.91% in body fat when 4mg was consumed. Similarly, fat mass was most prominent in the 4mg group, given that it went down by 6.68%. In the end, the team concluded that despite their findings, “Further studies are required to explore pharmacological, physiological, and metabolic benefits of both chronic and acute [Caps] consumption [3].”

One source that researched capsaicin supplements found that it may help boost metabolism. Furthermore, it was explained that this extract might work by increasing oxygen consumption and body temperature, which provides a slight advantage in burning more calories. Interestingly, a calorie deficit can be expected [4].


Chromium has improved insulin sensitivity and supports the metabolic breakdown of protein, carbohydrates, and fat intakes. A source that looked at the effects of Chromium on the body reported on a meta-analysis encompassing nine studies and a little under 630 obese or overweight participants. The researchers argued that any dose less than 1mg daily is unlikely to produce impressive weight loss results [5]. Yet another study reported similar findings, claiming that Chromium might have a marginal effect on overweight or obese people. What about healthy people? Let’s just say turning to Chromium even with regular exercise and a healthy diet will most likely do nothing [6].

Psyllium Husk

Psyllium husk is a shrub-like herb that is found mainly in India. Dietary supplements have been considered because it houses soluble fiber trusted to lower cholesterol levels [7]. If we were to consider soluble fiber alone, one source argued in favor of its consumption. Specifically, soluble fiber is believed to maintain healthy gut bacteria, promote fat loss by reducing appetite, and may go as far as triggering belly fat loss (if proper lifestyle decisions are made) [8]. That said, the direct effect of taking psyllium husk on weight loss does not appear to be extensively studied.


Ashwagandha is a renowned adaptogenic herb discovered to support the body responding to stress and anxiety. One study evaluated the safety and efficacy of a standardized root extract of Ashwagandha (300mg) twice daily. Fifty-two participants were split between the control and placebo groups. Three questionnaires were used to assess stress, food cravings, and happiness, while researchers also measured serum cortisol, body weight, and BMI. The findings suggest that “the treatment with Ashwagandha resulted in significant improvements in primary and secondary measures,” further pointing out that it is both safe and tolerable [9].


Finally, we have orlistat, a drug designed to treat obesity. One 54-week study on a mission to determine the efficacy and safety of orlistat in weight management of teenagers recruited 539 obese participants at 32 centers across the US and Canada. These individuals were given 120mg of orlistat or a placebo three times daily for one year, coupled with a mildly hypocaloric diet, exercise, and behavior therapy. The researchers concluded that “In combination with diet, exercise, and behavioural modification, orlistat statistically significantly improved weight management in obese adolescents compared with placebo. The use of orlistat for 1 year […] did not raise major safety issues although gastrointestinal adverse events were more common [10].”

Frequently Asked Questions About Weight Loss Supplements

Q: What are weight loss supplements?

A: Weight loss supplements are touted for their ability to promote weight loss by either preventing the absorption of carbohydrates, managing cortisol levels, limiting the effects of toxins in the body, curbing the appetite, or speeding up the metabolism, among other strategies. While evidence on its ingestion is mixed, people continue to take them, which to a large degree has to do with the ingredient list.

Q: Who should consider taking weight loss supplements?

A: People who are obese, overweight, or have failed to see results with healthy lifestyle choices may want to consider taking weight loss supplements. There are prescribed medications in the case of obesity, but of course, individuals may wish to consult a health practitioner before adding anything new. Other possible reasons include increased energy levels, suppressing appetite to reach a caloric deficit, etc.

Q: What are some common ingredients found inside weight loss supplements?

A: For the most part, weight loss supplements carry an array of plants, herbs, vitamins, and minerals. As this is being written, common ingredients found in such solutions include but are not limited to African mango, Beta-glucans, Caffeine, Capsaicin, Chromium, Conjugated Linoleic Acid (CLA), Fucoxanthin, Green Coffee Bean Extract, and Probiotics [11].

Q: Are weight loss supplements safe?

A: Generally speaking, weight loss supplements are deemed safe to take, especially when concentrations are relatively low. However, safety can vary from consumer to consumer as each person is unique in their health, body composition, allergies, etc. Once again, doing one’s due diligence and seeking professional advice is the best way to go about this.

Q: What side effects can be anticipated in taking weight loss supplements?

A: Common but manageable side effects include nausea, vomiting, constipation, fluctuations in appetite, and low blood pressure levels. However, serious effects include increased heart rate, pancreatitis, gallbladder disease, kidney problems, and the risk of developing suicidal thoughts [12].

Q: Are prescriptions needed for weight loss supplements?

A: No, weight loss supplements do not require prescriptions from a health professional. Most supplements only include vitamins, minerals, and other natural components that rarely need assessment. However, it won’t hurt to get a second opinion.

Q: Do weight loss supplements genuinely work?

A: It boils down to the ingredients and their respective concentrations. Clinical studies are typically conducted to answer this question. Regarding results, there’s always the participants, dosing, duration the ingredient is administered, and any other confounding variables to consider. If a component lacks such support, it might be safe to avoid it or seek professional opinions on ingestion.

Q: How should individuals approach weight loss?

A: The best approach is to ensure that it is sensical. By this, we mean following and being consistent with a healthy eating plan, achieving a nutritional caloric deficit, and regularly exercising. This not only helps with weight loss, but it can also go as far as improving mood and energy levels and possibly reducing the risk of developing health implications.

Q: Are weight loss supplements with caffeine the only effective ones?

A: Although most sources of caffeine have been proven to be effective for weight loss, it isn’t the only one. As seen in our top contenders, the strategy plays a whole lot of a difference. In cases where stress is high, caffeine might not work because it will only surcharge it some more. Ultimately, individuals need to reflect on their health before deciding on a weight-loss strategy. This will aid in choosing between several existing supplements in the market.

Q: Is it enough to just take weight loss supplements for results?

A: Of course not. A weight loss supplement alone might either elicit marginal results or none, for that matter. When individuals get off these supplements, the weight might be rebounded. Therefore, we encourage everyone to create an exercise plan and to remain consistent in choosing healthy lifestyle choices before adding a weight loss supplement to the equation.

Q: Which weight loss supplements are likely most helpful?

A: Refer to our top weight loss supplements for 2022 above. Some are more realistic and legitimate than others. Thus, more research will need to be conducted before narrowing down the options.

Q: Do weight loss supplements eliminate stubborn and belly fats?

A: It all depends on the ingredients and whether individuals actively seek healthy lifestyle habits to stick by. One source referencing existing science insists that eating plenty of soluble fiber, avoiding foods high in trans-fat, limiting alcohol and sugar consumption, eating meals high in protein, finding means of coping with stress, partaking in exercise, cutting back on carbohydrates, getting plenty of rest, having some quantity of healthy fish a week, eating foods with probiotics, fasting, and drinking green tea can further drive results [13].

Q: Can weight loss supplements be harmful?

A: Weight loss supplements can become harmful for people with existing medical conditions or those who abuse them. These solutions must be considered an add-on and never the main thing for weight loss results.

Q: Does my doctor need to know that I am interested in weight loss supplements?

A: As hinted at throughout this guide, individuals are highly recommended to discuss alternative weight-loss strategies (including supplements) with their physicians. The only reason we place so much emphasis on this is that no one knows a person’s health best like their physicians do, and discussing possible additions may bring light to both the risks and rewards!

The Top Weight Loss Contenders of 2022 Final Verdict

As we all enter yet another new year, the time to review and revisit last year’s goals has finally arrived. Many people are likely to have experienced hiccups in their weight loss goals, especially with the unexpected pandemic that still has some control over our lives. Fortunately, the entire world has joined forces in finding ways to live life to the fullest despite the hurdles, and the same should be applied to any weight loss journey, short- or long-term!

Having started with thousands of weight loss supplements, our editorial team managed to narrow down the list to 28, of which some are toppers, and others (based on popular demand online) carry very little substance. The exciting discovery (at least to our editorial team) is seeing the existence of diverse perspectives and strategies for weight loss. This is not to say that they all make sense, but luckily most do, which alone suffices to push research communities. Speaking of evidence, we must mention the ongoing need for more scientific research, as the weight loss industry remains one filled with doubts and unanswered questions.

Another profound key takeaway is that an equal number of scams have taken form in addition to robust solutions. Many people might find it challenging to decipher the good from the bad, but fortunately, scammers unknowingly leave hints behind. For instance, most popular supplements online lack transparency all-around, which forces us to question the entirety of the claims made and the solution. Besides transparency, company background, scientific evidence, clinical dosing, and advertised benefits are other basic requirements that everyone should seek. No matter if its metabolism boosters, appetite suppressants, meal replacement shakes or fat burners,

Finally, our ranking system doesn’t factor in health conditions or specific preferences. So, despite the existence of this guide, we hope that everyone will be digging more into the claims made and the supplement facts before placing an order. Until we provide some more updates, we believe that we’ve provided insight into essential steps to picking a possibly effective weight loss solution!


The news and editorial staff of Sound Publishing, Inc. had no role in the preparation of this post. The views and opinions expressed in this sponsored post are those of the advertiser and do not reflect those of Sound Publishing, Inc.

Sound Publishing, Inc. does not accept liability for any loss or damages caused by the use of any products, nor do we endorse any products posted in our Marketplace.